Category Archives: EZ 49 – Medical

Chemical Sensitivity

There are numerous factors that may participate in the development of hypersensitivity, to even minute levels of toxic and generally non-toxic chemical substances. Normal responses to subtoxic doses of chemical substances may be affected under the following conditions.

Genetic and individual abnormalities in enzyme and protein synthesis. Approximately 50% of the population are slow acetylators, example : they detoxify some chemicals slowly and thus are at risk to chemical sensitivity.

  • Poor diet and deficient nutritional states
  • Obesity and or increased fat / muscle ratio.
  • Age extremities-elderly and new born
  • Disorders of kidney and liver function
  • Gender of the individual.
  • Unstable hormone status.
  • Environmental stress conditions-heat, cold, dehydration, deficiency of oxygen (asthma), noise.
  • Achlorhydria is common in many chemical sensitive individuals and hence Vitamin B12 absorption may be impaired.

Chemical sensitivity or the allergic tendency of an individual can be inherited. However, allergic tendency, with no previous family history of allergy, can also be acquired in a number of ways. Hypersensitivity may follow viral infections such as mononucleosis or viral pneumonia, or severe emotional reactions such as grief. The most common incitement appears to be low grade, long term chemical exposure, although a short term high level exposure, such as seen in industrial accidents, may produce similar effects.

There is apparently no consistent pathway by which the immune system mediates chemical hypersensitivity or loses its control mechanism and begins to sensitize inappropriately to chemicals. The pathways used by the immune system to develop this phenomenon not only vary from chemical to chemical but from exposure to exposure, and certainly differ from individual to individual.

There are also the secondary effects or pathways of allergic inflammation to be considered, for instance, gastrointestinal symptoms range from vague indigestion to full blown colitis (inflammation of the colon). These may result in nutritional deficiencies.

The deficiencies begin with increasing the sensitivity of the immune system to food. Generalised inflammation of the gastrointestinal tract secondary to food sensitivity often causes poor nutrient absorption that leads to vitamin and mineral deficiency. Eventually the individual may become deficient in digestive enzymes, which in itself will initiate food intolerance or sensitivity.

With increasing vitamin and mineral deficiency and enzyme deficiencies, the end result is an inability to detoxify chemicals giving rise to more food and chemical sensitivities. Thus a vicious cycle is set that will only be overcome by judicious supplementation of vitamins, minerals and digestive enzymes.

Common Chemical Exposures that Cause Chemical Sensitivity

  • TERPENES – These are natural, volatile chemicals released from plants. They normally give the characteristic odour or scent of the plant, e.g., odour of fresh pine needles, orange, eucalyptus, cloves, jasmine. The level of terpene exposure depends on the time of year, highest concentration occurs during the warmest part of the year.
  • HYDROCARBON FUELS – natural gas, petrol fumes, coal gas, kerosene. Gas stoves or ranges can be a source of gas leakage in homes. Parking station attendants and petrol station attendance are in the high-risk group for this type of sensitivity.
    SYNTHETIC Synthetic ripening of fruits – such as bananas may liberate potentially harmful residue of the ripening gas ethylene. Commercial coffee that is gas roasted is another example.
  • FORMALDEHYDE PRODUCTS – are notorious for their adverse reactions in sensitised individuals. Hidden sources of formaldehyde exposure are plastics, chipboard, home insulating material (foam type), nylon carpets, mouth washes, wood veneer, latex paints, detergents soaps, hair setting solutions and shampoos.
  • PERFUMES – heavily scented cosmetic, deodorants, sprays, tobacco, scented soaps, nail polish, strong cleaning solvents and synthetic clothing or garments have all been implicated in chemical sensitivity. Beauticians and hairdressers should be aware that some of their symptoms such as headaches, irritability and fatique may be due to scented products.
  • PESTICIDES – weedicides and agriculture chemicals must also be considered as potential problems in some individuals.
  • ARTIFICIAL – colourings and flavourings.
  • CHLORINATED WATER – is also a common culprit.Symptoms of chemical sensitivity vary quite widely and include headache, irritability, fatigue, hyper or overactivity, restlessness, anxiety, sluggish thinking, malaise, muscle pain, arthritis etc.

Nutrients That Decrease Chemical Sensitivity

  • Molybdenum are enzymes involved in the detoxification of various aldehydes, sulphites & nitrates.
  • Glycine, Taurine, BCAA, Methionine, are amino acids associated with the removal of toxic chemicals and metabolites from the body.
  • Thiamine (Vit B1) helps those excess intake exposure to formaldehyde, alcohols, glycols and it is also important in energy production. A relative deficiency will cause tiredness, weakness and anxiety.
  • Pyridoxine (B6), 60 percent chemically sensitive patients are deficient in B6, which is pyridoxal – 5 phosphate, which can be overwhelmed by exposure to aldehydes. Drugs such as contraceptive pills, amphetamine, chlorpromazine can all lead to a relative B6 deficiency.
  • Choline – ingestion of a diet deficient choline has major consequences that include hepatic, renal, memory impairment and growth disorders. All are seen in some chemically sensitive patients.
  • Folate B12 – chemically sensitive individuals are low in folate and 15% are deficient in Vit B12. Many medications such as aspirin, oral contraceptive and anti-convulsant interfere with absorption and metabolism.
  • Magnesium – Approximately 40% of chemically sensitive individuals are magnesium depleted. As magnesium involved over 500 enzyme systems.
  • Substances that deplete magnesium are pollutants, alcohols, diuretics, steroids, glucose, phosphate depletion and pesticides.

Nutritional Advice

  • Filter or boil all drinking water
  • Use toxic cleaning products sparingly
  • Reduce use of plastics, toxic paints and varnishes. When painting use odourless alkali based paints
  • Do not to wear synthetic under garments or clothes. Cottons & woollens are usually safe.
  • Do not use kerosene heaters, heating should be solar based or electrical.
  • An electric stove is preferable to a gas stove, and if not possible, ensure adequate ventilation within the cooking area.
  • Insulation material and floor coverings should be inert. Preferably hard, inert materials such as stone, terrazzo, hardwood, cement, brick and terracotta tiles should be used for flooring. Be careful of wool carpeting with latex or rubber backing.
  • Soft plastics, such as plastic bags, wrapping, plastic containers, and other plastics should be removed from the home. Use glass containers.
  • Remove any synthetic or rubber furnishing in the bedroom. Use cotton pillows, mattresses. Electric blanket should not be used. Cane hardwood, leather, wool or other fibre should be used in furnishings.
  • Other sources of chemical exposure are from chemicals released from glued parts and grouting, particularly when heated, chemicals used in hobbies such as photo copying machines, pesticides used indoors or in the garden, timber impregnated with chemicals, tobacco smoke.
  • Avoid all formulated foods or drugs that contain artificial flavourings, colouring or chemicals.

Fertility & Gynaecology

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Dr Ng Peng Wah
Fertility Specialist, Obstetrician and Gynaecologist Royal College of Obstetricians & Gynaecologists in United Kingdom

About Dr Ng Peng Wah
1995 – First Gamete Intrafallopian Transfer (GIFT) baby boy was born.
1996 – First In-Vitro Fertilisation (IVF) twins baby boys were born.
1999 – First Intracytoplasmic Sperm Injection (ICSI) twins baby boy and girl were born.
2001 – First frozen embryo transfer (FET) baby girl was born.
2004 – First Testicular Sperm Extraction (TESE) baby boy was born.
2007 – First blastocyst culture twins baby boy and girl were born.
From 2011 to 2012, he also served as the President of the Malaysian Society for Assisted Reproductive Technology (MSART) and remains a Committee Member till today.

1995年–首例配子输卵管内植入 (GIFT) 男婴诞生。
1996年–首例试管婴儿 (IVF) 双胞胎男婴诞生。
1999年-首例胞质内精子注射 (ICSI) 双胞龙凤胎男女婴诞生。
2001年-首例冷冻胚胎移植 (FET) 女婴诞生。
2004年-首例睾丸精子提取 (TESE) 男婴诞生。
从2011年到2012年,伍医生也担任马来西亚辅助生育技术学会 (MSART) 的会长,直至现在依旧是该学会的委员会成员。

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Penang, which has been designated as UNESCO World Cultural Heritage Site, is repeatedly considered one of the most desirable tourist destinations in Asia. With medical tourists increasingly seeking for medical treatment in Malaysia, it is clearly seen that the healthcare services offered and delivered in Penang is of international standards.


Dr Ng Peng Wah, a renowned and familiar name in this region’s IVF industry has over 28 years of experience in the field of obstetrics, gynaecology and fertility. With his talents and experiences, he has numerous successes to his name and has helped thousands of patients in delivering their dreams.

Genesis IVF which is co-founded and led by Dr Ng, has quickly become the undisputed leading IVF centre in the medical tourism industry dedicated to assist patients overcome infertility. We sat down with him for a short interview.

伍柄华医生 (Dr Ng Peng Wah) 这个耳熟能详的名字,在俗称“试管婴儿” (IVF-体外受精联合胚胎移植技术) 和妇产科辅助生殖科领域拥有超过28年的经验。他的杰出才能和娴熟丰富历练,创造了许多成功的案例,并协助上千名病患实现他们的生育梦想。

由伍医生共同创立并领导的 Genesis IVF,迅速成为医疗旅游行业中一路领先的辅助生殖专科中心,致力于协助病人克服不育症。我们这次也捉紧机会和他简短会谈。

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EZ : We’ve seen an influx of international patients coming to Malaysia for better medical treatment. Has it been the same for fertility medicine?

NPW : Indeed, it has. In 2016, Malaysia is recorded to have earned RM1 billion from healthcare tourism and expected to achieve RM1.3 billion in 2017. In our centre, over 60% of our patients come from overseas. It is very assuring to know that there are so many international patients who have confidence in our IVF centre.

EZ : In your many years of practice, what are your thoughts on the Malaysia’s assisted reproductive technology, in comparison with the region?

NPW : Malaysia’s medical capabilities has seen huge improvements over the last few years. For example, Malaysian IVF in the 80s had only around 15% success rates. Today, we have reached 80% in embryo transfers. Malaysia is also now deemed having one of the most comprehensive and complete all-in-one fertility services in Asia and Australia.

EZ : What drove you to establish Genesis IVF?

NPW : Throughout the years, I’ve seen patients from all walks of life and the joy of finally helping patients overcome infertility is the greatest pleasure I can experience. I believe with Genesis IVF, we are providing a centre that has an all-inclusive service for all their infertility needs. Our patients are able to receive first class comfort and professional care.

EZ : We understand Genesis IVF has its very own laboratory. Can you tell us more?

NPW : Of course! Genesis IVF has its own team of talented embryologists and geneticists. We are not only focused on increasing the chances of couples to have a baby, but we believe in creating healthy future generations. Our lab is fully capable of providing Pre-implantation Genetic Screening (PGS) as well as Pre-implantation Genetic Diagnosis (PGD) to select the best healthy embryo for each couple.

With PGS, we are able to analyse the 23 pairs of chromosomes in the embryo’s DNA and increase the chance of pregnancy while reducing the risk of miscarriage or risk of having a chromosomally abnormal child.

PGD is recommended for couples who have a known genetic abnormality, such as Thalassaemia. With PGD, we are able to help reduce the chances of their children inheriting any genetic abnormalities.

EZ : Many couples are getting married and planning to start a family later these days. What is your advice?

NPW : While there is a saying that “30 is the new 20”, our body’s biological age hasn’t changed much yet. Studies have shown women above the age 35 have a significantly increased risk of infertility.

Fortunately, we are here to help. Our modern lifestyle is also a contributing factor to infertility. Remember to take everything in moderation and seek a balanced diet.

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EZ : 我们看到大量的国际病患者前来马来西亚寻求更好的医疗服务,对于生育医学领域来说也是这种情况吗?

NPW : 确实。在2016年,马来西亚的医疗旅游收入超过10亿令吉。而在我们的医疗中心,60%以上的病人皆来自海外。我们也非常肯定,许多国际患者对于 Genesis IVF 专科中心充满信心。

EZ : 依据多年的实践经验,你对马来西亚辅助生育技术有何看法?与该区域之间相比?

NPW : 马来西亚医疗技术质量在过去几年里取得了巨大的进展。例如,我们80年代试管婴儿成功率只有15%左右。今天,胚胎移植率已达到80%,同时也被认为是在亚洲与澳大利亚区域间具备最全面生育服务的国家之一。

EZ : 驱使你创立 Genesis IVF 的动力是什么?

NPW : 多年来我接触到形形色色的患者,帮助他们克服不育症的喜悦,让我能感受到的美好快乐。我相信 Genesis IVF 中心提供全面的辅助生殖疗程。我们的病人在最佳的舒适环境和得到专业照顾。

EZ : 我们知道 Genesis IVF 有本身独立的实验室。对此我们可以了解更多吗?

NPW : 当然!Genesis IVF 拥有一组具备天赋的胚胎学家和遗传学家的团队。我们不仅关注增加夫妻孕育孩子的机会,而且我们确定创造健康的后代。我们的实验室拥有提供胚胎植入前遗传基因筛查 (PGS) 和胚胎植入前遗传基因诊断 (PGD) 的实践能力,为每对夫妇遴选出最佳状态的健康胚胎。



EZ : 对于那些近期结婚并计划组织小家庭的夫妻,你的建议是什么?

NPW : 纵然目前有个说法是“30代是新20代”,但我们的身体机能年龄还是无太多变化。研究证明,35岁以上的女性面临不孕的风险大幅度增加。幸运的是,我们可提供帮助。现代人的生活方式也是导致不育症的因素之一,记住必须坚守节制的生活习惯和均衡饮食。

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