Category Archives: Medicines & Sciences

Features medical breakthroughs and the latest in healthcare through informative articles

Candidiasis

by Dr. Mecherl Lim

MD (MA) Naturopath (ND), Holistic Kinesiology


Vaginal candida (genital candidiasis, or thrush) is an overgrowth of Candida Albicans, a yeast-like fungus that affects the area in and around the vagina, vulva and rectum.  In severe cases, the rash can spread to the thighs and buttocks.  About 30 percent of reproductive -age women have some candida in the vagina but only half of them have symptoms and around five percent have recurrent problems.

WHAT ARE THE SIGNS AND SYMPTOMS?

The early symptoms are redness, swelling and irritation.  In severe cases, the rash areas can become cracked, itchy and burning,m with a whitish or slightly yellow discharge and occasionally a sour milk odour.  There may be pain when urinating and during intercourse.  Men often carry the infection on the penis but may not have symptoms.  Symptoms in men usually include soreness, redness, itching and fissuring of the penis.

HOW IS IT DIAGNOSED?

A doctor takes a swab which is then examined in a pathology laboratory.  There is an also a medical blood test to see if the candida has spread throughout the body (known as systemic candidiasis) but my experience is that this test  is not conclusive and candida fungi may live in the human body without causing any apparent problems.

WHAT CAUSES IT?

The cause is primarily an overgrowth of Candida albicans, and it’s an increasing problem, with significantly more case caused by other species of Candida.

Conditions associated with candida include diabetes, pregnancy, suppressed immune function and the use of antibiotics or cortisone drugs.  Hormone changes tend to make women more susceptible to infection, which explains why candida occurs during pregnancy and with some oral contraceptives and hormone replacement therapy Temmerman  MI, Nelis HJ, ‘Prevalence of vulvovaginal candidiasis and susceptibility to fluconazole in women’ American Journal of Obstetrics and Gynecology 187: (2002): 569-74.

Candida seems to occur more frequently among wearers of pantyhose and those who use marijuana, malnutrition, alcoholism, bath additives and vaginal deodorisers may increase the risk.  Sometimes women seem to get candida when they are severely stressed, depressed or not eating properly.  I have seen cases that may link to antacids and antidepressant drugs.

You can pass on the infection to your partner and this may cause him to reinfect you, even if he doesn’t appear to have any symptoms. Condoms should be used when infections are present.

Various resistant strains may result from the increasing use of short course antifungal medications, but I don’t know if resistant strains occur as a result of ineffective natural treatments. See your practitioner if you are experiencing side effects from any treatment or if the condition is worsening, otherwise, it’s generally advisable to complete the prescribed course.

HOW ALLOPATHY DOCTORS TREAT?

Medical/pharmaceutical treatments include over the counter and prescribed topical antifungal creams pessaries and ovules. Oral antifungal pharmaceuticals are prescribed when topical remedies have not been successful but these may not give a permanent “cure” in the majority of recurrent cases.

Boric acid pessaries. Basically, the treatment is 600mg of boric acid in a size of 0 gelatine capsule inserted in the vagina last thing at night for 10 to 15 days.  This treatment is 80 percent successful in eradicating Candida glabratta, a resistant strain.  Boric acid is a lethal poison at a dose of 15-20g and is never taken orally.  You absorb a little through the vaginal wall.  A pharmacy may be able to order in a course of boric acid pessaries.  This treatment  may irritate the area around the vagina and you may need to apply a soothing cream or almond oil externally just after inserting the pessary.

THE HOLISTIC APPROACH

First, get a medical diagnosis, because some similar symptoms occur in eczema and various infections.

  • Oral, antifungal medicinal
  • Oregon grape herbs
  • Grapefruit seed extract
  • Pau d arco
  • Goldenrod
  • Thuja
  • Myrrh
  • Echinacea
  • Aloe
  • Green Walnut Hulls
  • Goldseal
  • Corn Silk
  • Olive Leaf

Herbalists generally prescribe a selection of these and may include herbs to strengthen the immune or nervous systems, such as astragalus, cats claw or ginseng.

NATURAL TOPICAL REMEDIES

Various natural pessaries and ovules are available, including tea tree oil, golden seal, calendula or lactobacillus.

Caution: Topical medical and natural remedies can aggravate, so always test everything- first on the inside of the elbow and, if this is OK, apply a tiny portion around the vaginal area. I don’t recommend douching because this depletes natural vaginal secretions and may upset the bacterial balance. Do not persist with natural therapies if they don’t work within one week because, aside from the pain and stress, you develop a secondary infection.

HOW CAN YOU PREVENT IT?

Candida feeds on sugars and like warm, dark, moist places.

  • Avoid all refined sugars and obviously high-sugar foods such as cakes, fruit juices and dried fruits.
  • Wear cotton undies and avoid tight jeans and trousers.  Very tight trousers cause heat and may rub the vaginal tissue, causing slight damage and making it more prone to infections. (Very tight clothes can also cause a backache and may contribute to pelvic congestion and varicose veins.) Perhaps at home wear a skirt and no undies to keep the area reasonably cool and reduce sweating.
  • Wipe from front to back after going to the toilet.
  • Urinate before and after sex.
  • Use minimal soap in the vaginal area, buy a product that is unscented and ph balanced.
  • The incidence of candida is higher in the tropics, so perhaps plan cool climate holidays.
  • If you are taking antibiotics ( a common cause of candidiasis), use Dr Mecherl PROFLOR A, contains Lactobacillus GG, Lactobacillus Plantarum, Lactobacillus acidophilus NCFM, & Rhamnosus LGG, Colostrum.because these strains seem to work more effectively to offest antibiotic side effects.  I suggest two or three doses daily of the Proflor A as far away in time as possible from the doses of antibiotics. The will ensure that a least for part of each day you have some healthy bacteria in your system. Continue with the Proflora A for a week after you finish the antibiotics.  One trial indicated that Lactobacillus was not effective, but this is not my experience and it may depend on the strain.  Two trials have indicated plain yoghurt may be helpful as preventive but check the labels for sugar content.

DIET

Some of my patients advise they have overcome recurring vaginal candida by following a strict diet that avoids not only sugars but also all the following foods.

  • All yeast bread, rolls, doughnuts and any product or supplement that contain yeast.
  • All cheese, including cottage, ricotta and soy cheese
  • Pickled and smoked foods, including corned beef and bacon
  • Beer, wine, ginger beer, sherry, port
  • Vinegar and any food that contains vinegar
  • Mushrooms
  • Soy sauce, tamari, miso, tofu
  • Vegemite, Marmite, Bonox, stock cubes
  • Dried and canned fruit
  • Melons and peanuts (because of their natural moulds)
  • Leftover foods.

However, this dietary program doesn’t make sense to me because there’s no evidence that one particular fungus, mould or fermentation process will cause a detrimental overgrowth of another fungus. In fact, some practitioners recommend yoghurt, miso, a little vinegar, olives and traditional coleslaw as part of a preventive program.  However, if you are desperate you may want to try this avoidance program for one month, evaluate, and then reintroduce the items one at a time in small quantities. Some women report they can tolerate some of these foods in small quantities.

HERE ARE MY DIETARY RECOMMENDATIONS :

  • Use wholegrains because these are not readily converted to glucose and have other advantages: rice fibre, for instance, contains gamma-oryzanol, which is somewhat antifungal.
  • Some culinary herbs have antifungal properties, so use these generously in your cooking. The list includes cinnamon, thyme, turmeric, rosemary, garlic, mustard, oregano, lemongrass and winter savoury.
  • Foods in the cabbage family are recommended.

GOOD ADVICE :

For persistent or severe vaginal candida get practitioner help because the infection needs to be eradicated.


Dr Mecherl Lim

An Intuitive Medical Practitioner in Alternative Medicine (MD) (MA), Naturopath (ND), Holistic Kinesiology (HK), and Functional Medicine (FM)

Next  No 53 Issue : ENDOMETRIOSIS

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Women’s Reproductive Health

Part 2 : PERIOD PAIN (DYSMENORRHOEA)

by Dr. Mecherl Lim

MD (MA) Naturopath (ND), Holistic Kinesiology


This is lower abdominal pain that commences just before or during menstrual flow, the first 24 hours being the most painful. 

About 70 percent of women experience some degree of menstrual pain.

WHAT ARE THE SIGNS AND SYMPTOMS?

The pain may be gripping, cramping or a constant ache, and it ranges from mild to severe.  Sometimes it spreads to the back and down the legs.  Period pain may sometimes be accompanied by scanty or heavy flow with clots, headaches, nausea, vomiting, constipation, diarrhoea, sore breasts or dizziness and fainting.

HOW IS IT DIAGNOSED?

A medical diagnosis is required to find out if the pain is menstrual or something else.  Primary dysmenorrhoea is normal menstruation that is accompanied by pain.  Secondary dysmenorrhoea is linked to a cause such as endometriosis, fibroids or polyps.

WHAT CAUSES IT?

Primary dysmenorrhoea is caused when the uterus contracts to eliminate its lining.  Women with period pain probably have high levels of prostaglandins and these compounds over stimulate the uterus.

Secondary dysmenorrhoea has a medical cause such as fibroids (obstructive internal uterine growths) that cause the uterus to contract more powerfully than normal.  Intrauterine contraceptives are also linked to period pain.

HOW ALLOPATHY DOCTORS TREAT IT?

Primary dysmenorrhoea

  • Painkilling drugs, such as paracetamol
  • Prostaglandin inhibitors, such as ibuprofen
  • Oral contraceptives often eliminate period pain

Secondary dysmenorrhoea

The medical treatment depends on the cause and may involve hormones, anti-inflammatory pharmaceuticals or surgery.

PHARMACEUTICAL USE

All drugs have a long list of cautions and adverse effects, as you will see from package inserts or by looking at the MIMs Annual in your library.  Not everyone experiences side effects and you may need to take a strong, quick acting medication for severe symptoms and particularly for pain. If a few over the counter painkillers, such as paracetamol, prevent period or other pain, then that’s the simplest most effective and economical treatment-and it’s unlikely that you will experience side effects from taking, say, two to six tablets a month.

THE HOLISTIC APPROACH

Bed rest with abdominal heat (such as a hot water bottle) is a standard recommendation. This works better if you gently massage about six drops of lavender oil onto your abdomen before applying the heat and lie on your back with a large pillow under your knees.  A combination of eucalyptus and peppermint oil also helps some women and this combination may prevent a headache if you put a few drops on the back of your neck and one drop on the end of your nose.

Herbs : Specific herbs such as cramp bark and wild yam, Chaste tree, Dong Quai, Red Raspberry leaf, False Unicorn, Feverfew, Cinnamon helps to relieve pain and inflammation and reduce the need for pharmaceutical painkillers.

You can also use Dr. Mecherl SHE 18 which is already a combination of the above herbs and you can also see the tea recipe under “Endometriosis” Supplements.

A combination of evening primrose and fish oil works well (and even more so if vitamin E is in the formula), such as Dr Mecherl Femi Vita M or Femi HH.  Neuromous (Magnesium) is sometimes helpful,  I recommend these daily for three months, and if effective relief is relieved, reduce the dose to two weeks, then re-evaluate every few months to find the lowest helpful dose.

This type of schedule works for a number of natural remedies and the aim is to find the lowest helpful dose that works in your case. Subsequently, some women stop taking all remedies, although their pain may recur following illness or major stress.

Other remedies are exercise such as easy yoga may help ease abdominal tension and improve blood flow and therefore reduce pain.  Some women say a glass of wine or a nip of brandy helps!

HOW CAN YOU PREVENT?

Regular exercise throughout each month generally relieves congestion and stress.  Also, you will see under “Premenstrual syndrome (PMS) that a scientific trial showed that a vegetarian diet helps reduce period pain.

GOOD ADVICE

Always do something about pain, because it increases inflammation, prevents sleep, may cause depression and blocks enjoyment.


 

Next No 52 Issue : CANDIDIASIS
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Why are we so afraid of Infertility? Dispersing the taboo of infertility 为何我们对不孕症如此恐惧? 解开不孕症之谜

Dr Ng Peng Wah

Fertility Specialist, Obstetrician and Gynaecologist Royal College of Obstetricians & Gynaecologists in United Kingdom


We sat down with Dr Ng Peng Wah from Genesis IVF and Women’s Specialists to discuss infertility and the taboo surrounding it. Genesis IVF is Penang’s premiere IVF centre aimed at providing effective infertility treatments with world-class facilities to help patients deliver their dreams of having a baby.

我们与起源妇产助育专科中心(GenesisIVF)创立者兼妇科专家伍柄华医生(Dr Ng Peng Wah)讨论不孕症之谜。Genesis IVF 是槟城首屈一指的资深人工试管婴儿(体外受精联合胚胎移植技术)专科医疗中心,旨在提供先进的助孕治疗技术和世界级的硬体设施,协助患者实现生育梦想。

Q: What is infertility and what are the steps someone who has problems conceiving should take?

NPW: Infertility as defined by World Health Organisation (WHO) as the inability to achieve pregnancy after trying for 12months without using contraceptives. If female patients are above the age of 35, they are considered suffering from infertility if they have been trying for 6 months.

The best action to take is also the most direct one – patients should come to see a fertility specialist so that the cause of infertility be identified so that a proper treatment can be attempted.

Q: What are some common causes behind infertility and the treatments to overcome it??

NPW: Infertility causes are varied but it can equally be male or female factors.

A common problem for male infertility is the inability to produce an adequate amount of viable sperm due to endocrinal, physical, chromosomal or other issues.

One of the most common female infertility problems is caused by ovulation. Ovulation problems are often caused by polycystic ovarian syndrome, which is a hormone imbalance problem that causes infertility. Another common ovulation problem is primary ovarian insufficiency (POI), which occurs when a woman’s ovaries stop working properly.

A woman’s age plays an important role in infertility as it has been statistically proven that women over the age of 35 face increased infertility problems. One of the most effective methods is In-Vitro Fertilisation (IVF) in conjunction with other technologies to augment a patient’s pregnancy rates. The beauty of IVF is that it helps overcome many infertility problems including: Blocked tubes, polycystic ovary syndrome, endometriosis, premature ovarian failure as well as low sperm quality.

Q: What are the technologies that can augment a patient’s pregnancy rates?

NPW: We employ techniques such as Intra Cytoplasmic Sperm Injection (ICSI) for patients suffering from low sperm quality to overcome male infertility by manually injecting a sperm into the egg to eliminate the problems of low motility sperm.

Additionally, we have Preimplantation Genetic Screening (PGS) offered to patients to ensure only chromosomally normal embryos are transferred into the mother’s womb. Embryos with abnormal chromosomes usually do not survive pregnancy; even if the pregnancy is successful, the child born with chromosomal abnormalities will be born syndromic such as Down Syndrome, Edwards Syndrome, Patau & Klinefelter. Chromosome defects are one of the most common causes for miscarriage, especially for women over the age of 35.

Q: Before we end do you have any advice for couples facing infertility?

NPW: As a fertility specialist, it is our duty to advocate and educate the public that Infertility is a disease and like any other diseases, couples with infertility should seek out treatment to overcome this disease.

问:何为不孕症?面对不孕我们应该采取什么措施?

NPW : 世界卫生组织 (WHO) 所定义的不孕不育是指在没使用任何避孕药具,备孕12个月后依旧无法怀孕。如果女性患者年龄在 35 岁以上,已经尝试了6个月仍无法怀孕,就会被认为是不孕症。最佳也是最直接的措施——患者应该咨询生育专家,这样除了可确定导致不孕的原因,还可进行适当的治疗。

问:不孕症常见的原因和疗法?

NPW : 不孕的因素多种多样,皆可发生在男性或女性身上。男性不孕常见原因是由于内分泌、生理、染色体等问题而不能生产足够数量的精子。而导致女性不孕的常见原因之一是排卵问题,通常由多囊性卵巢综合征,激素失衡而导致不孕。其它的排卵问题原发性卵巢功能不全 (POI),这种病例是卵巢停止正常运转。而女性的年龄在不孕因素中有着关键联系,统计数据证明,35岁以上女性面对不孕问题的机率较高。试管婴儿或体外受精 (IVF)是最有效疗法之一,结合其他的技术将可提高患者怀孕率。试管受精的好处在于可协助克服许多不孕问题,包括:输卵管堵塞、多囊卵巢综合征、子宫内膜异位症,卵巢早衰以及精子质量不理想。

问:有什么技术可以提高病人的怀孕率?

NPW : 我们对精子质量不理想的患者采用单精子注射 (ICSI) 等技术,朝卵子中注入精子,解决精子活跃度低下的问题,克服男性不孕。此外,我们还为患者提供移植前基因检测 (PGS),确保只有染色体正常的囊胚被移植到母亲的子宫中。染色体异常的胚胎通常不能存活;因为即使成功怀孕,染色体异常的孩子也会出现如唐氏综合症,Edwards Syndrome, Patau & Klinefelter 等综合征。染色体缺陷是导致流产的常见原因之一,尤其是35岁以上的女性。

问:在我们结束讨论之前,对面临不孕的夫妇有何建议?

NPW : 作为一名生殖课专家,我们有义务向公众宣导和传达其实不孕症是一种病症,就像其他疾病一样,不育夫妇应该寻求医生进行治疗。

WOMEN’S REPRODUCTIVE HEALTH

by Dr. Mecherl Lim

MD (MA) Naturopath (ND), Holistic Kinesiology


I would like to overview 5 common women’s reproductive health problems and aim to assist you in making informed decisions about treatment options and to suggest ways you can incorporate practical preventive strategies into your lifestyle.

Fortunately, we live in a time when women’s  health issues are more openly discussed and it’s our hope you’ll perpetuate the wisdom gleaned from the following pages by sharing this with the women-men-in your life.

PREMENSTRUAL SYNDROME (PMS) – A disorder associated with a cluster of symptoms is classed as a syndrome. About 90 percent of menstruating women experience mood changes, fluid buildup and various other problems two to 14 days before menstruating. These symptoms may disrupt everyday life in about 10 to 20 percent of women.

WHAT ARE THE SIGNS AND SYMPTOMS?

More than 100 different symptoms of PMS have been reported.

The most common:

  • Irritability or aggression,
  • Depression and low self-esteem,
  • Insomnia,
  • Sore breasts,
  • Abdominal bloating/constipation,
  • Headaches.
  • Food cravings and binge eating,
  • Back and muscle pain,
  • Pelvic discomfort &
  • Reduced concentration, “fuzzy” brain.

HOW IS IT DIAGNOSED?

A diagnosis is based on the pattern of symptoms experienced by women.  Sometimes medical hormone test is used.

WHAT CAUSES IT?

Australian medical experts say the cause of PMS is unknown but there is some link to emotional, physical and hormonal factors.

POSSIBLE CAUSES INCLUDE :

  • Reproductive hormone imbalances may relate to relative levels of estrogen, progesterone, prolactin, and testosterone – or their breakdown products (metabolites). It is possible to have a normal level of a particular hormone but it may be blocked because it interacts with something else.
  • Cortisol, the stress hormone, increase blood sugar levels, which gives you a boost. However, when the levels decrease, you may feel tired and crave sugary foods.
  • Aldosterone, another adrenal hormone, affects the minerals  (electrolytes) and fluid balance.
  • Stress affects reproductive hormones, and your hormones may fluctuate more than “normal”. All changes are somewhat stressful and one theory is that when the levels of any hormone drop, you may experience “withdrawal”.
  • Other causes may be nutrient deficiencies or excesses, prostaglandin deficiencies or excesses, lowered natural opiates or neurotransmitters and live /intestinal malfunctions.

HOW THE DOCTORS TREAT IT :

Current medical options include hormone therapy, oral contraceptives, antiprostaglandins (for pain), antidepressants, diuretics, and bromocriptine. Natural progesterone is probably the safest medical option, but scientific trials show it’s no better than placebo (Wyatt K, Dimmock P, Jones, et al, “Efficacy of progesterone and progestogens in management of premenstrual syndrome: a systematic review” British Medical Journal 323 (2001) : 776-80.

In a scientific study of isoflavones (which are commonly isolated from red clover or soy) for periodic breast pain (cyclical mastalgia), after three months of treatment nine out of 12 women had less pain compared with two of six on placebo. The researchers stated the isoflavones act as weak anti-estrogen and have no side effects. I suggest a more economical way of getting a good dose of isoflavones is to have a quarter of a cup of (phyto Nutri) alfalfa, mung beans or other sprouts daily

THE HOLISTIC APPROACH HERBS :

  • Chast tree produces a significant decrease in PMS symptoms compared with placebo and this has been verified in the least 15 scientific trials. Most trials lasted about three months and used low dose, guaranteed potency or standard products. example Dr Mecherl SHE 18.
  • St John wort, if the main symptoms are depression.
  • Ginkgo, for reduced concentration and breast tenderness.
  • Feverfew, to help prevent headaches.

SUPPLEMENT :

  • Vitamin B6 (pyridoxine) and magnesium have helped women more than placebo, although vitamin B6 alone is not as successful as a chaste tree (She18). (Common doses are 50mg of pyridoxine and 20mg of magnesium.) *Evening primrose oil is helpful when women are deficient in essential fatty acids or have problems with oil metabolism.
  • Calcium maybe helpful but depends on diet and absorption. Some women consume six serves of dairy foods daily (equivalent to about 3000mg of calcium), which is excessive and likely to interfere with other nutrients as well as being too alkaline.
  • Taking a multivitamin/mineral supplement improves symptoms in 17 out of 23 women. This is not surprising because when women with PMS are tested, they invariably have low levels of a number of vitamins and minerals compared with women who have minimal or no PMS.

DIET

In a dietary trial for premenstrual symptoms (PMS) and period pain, 33 women followed a low-fat vegetarian diet for two menstrual cycles. The diet consisted of grains, vegetables, legumes and fruit with no restrictions on quantity. (Animal products, added oils, fried foods, avocados, olives, nuts, nut butter and seeds were eliminated.) The symptoms and pain fell significantly.

This diet would provide a high level of phytoestrogens and fiber and consequently, the body’s own estrogen uptake would be lowered and constipation/ bloating would be reduced. However, in the long term, it would cause vitamin B12 deficiency unless a supplement was taken. Eggs, lean meat, yogurt, olives, avocados, nuts, and seeds are health-enhancing foods that should be eaten regularly in moderate quantities (besides, they re enjoyable to eat and also allow you to socialize normally!).

Dietary surveys indicate women with PMS tend to eat significantly more junk food, notably sugary, fatty and salty foods. Perhaps this indicates a need for energy or consolation? On the other hand, dieting makes you hungry, lowers your blood sugar, your brain doesn’t work properly, you feel tired and you grab foods to give you quick relief. You need energy before you can achieve anything. Have a large mixed vegetable salad or soup with lunch and plenty of cooked vegetables at night to help fill you up and to avoid weight gain.

HOW CAN YOU PREVENT IT?

  • Have varied, non-restrictive diet using foods in a natural a state as possible.
  • Avoid refined carbohydrates (sugars, white flour and so on) and fad diets.
  • Lack of essential fatty acids is linked to PMS, weight gain, excessive mood changes, lowered concentration, joint and muscle pain, food cravings, fatigue and breast tenderness. The best way to get essential fatty acids is from foods such as fish (especially herring, sardine, and salmon), nuts and seeds, virgin olive oil and avocado.
  • Don’t use foods for reward or consolation.  Find other strategies such as outings, music, aromatherapy, massage or books.
  • A study showed that jogging or walking about 2.5 kilometers daily for six months give significant reductions in fluid retention, breast tenderness, and the overall symptoms picture. If you are jogging or doing aerobic exercises, make sure you wear a firm support bra or you may aggravate breast soreness.

GOOD ADVICE :

A whole food diet (with occasional treats), regular exercise and enjoying your life are basic PMS treatments.

ALPHA FERTILITY CENTRE

Dr Leong Wai Yew, Dr Haris Hamzah, Dr Tan Chong Seong, Dato’ Dr Colin Lee Soon Soo


Alpha Fertility Centre (AFC) is set up and run by leading medical specialists and embryologists responsible for numerous fertility achievements both in the regional and global arena. This purpose-built advanced fertility centre located in Selangor, Malaysia is fully equipped with modern comprehensive range of fertility treatment options; including but not limited to PGD/PGS with Ion Torrent NGS, Embryoscope+, Embryo Freezing using Cryotec® that gives 100% post thaw survival rate, Egg donation program, and many more (refer to website : http://www.alphafertilitycente.com)

As the name ALPHA suggests, the Medical Specialists and Staff at ALPHA have successfully innovated numerous fertility treatment procedures that led us to achieve many FIRSTS!

In addition to achieving numerous fertility achievements in Malaysia and Singapore, we have also achieved and innovated many world’s FIRSTS.

In the tradition of FIRSTS, we are committed to put You and Your Fertility needs as our FIRST PRIORITY. We do this by treating every couple individually; crafting truly personalised, tailor-made patient care IVF treatment programme to cater for Your specific needs.

Let us be Your dedicated partner in making Your fertility journey a successful one, leading to a bundle of joy for You and Your Family!

Alpha Fertility_Lab.jpg

阿儿法国际辅助生殖中心 (Alpha Fertility Centre) 由一组权威生殖专科医生和资深胚胎学家/基因学家组成,造就了区域、乃至全球辅助生殖领域硕果累累。

这家位于马来西亚雪兰莪州的辅助生殖中心拥有现代化的综合治疗方案与技术。包括以 Ion Torrent NGS 次代基因测序进行胚胎移植前基因诊断和检测 (PGD/PGS) 、升级版胚胎培育器、使用100%冷冻-解冻存活率的 Cryotec® 冷冻技术、卵子捐赠计划和更多高端技术。具体详情请浏览www.alpahfertilitycentre.com 网站。

【阿儿法 – 希腊字母象征第一】顾名思义,阿儿法医疗团队已成功开创和引进多项科技与技术,让中心满载多项首创荣誉。

除了在马来西亚和新加坡缔造多项助孕成就以外,还实现无数全球首创。

秉持“第一”的原则,阿儿法承诺把您的生育需求为己任。为每一位疗程中的夫妇的特殊状况与需求制定个人化的治疗方案。

让阿儿法成为您的伙伴,助您安心踏上试管之旅,实现更完美家庭的理想。

Chemical Sensitivity

There are numerous factors that may participate in the development of hypersensitivity, to even minute levels of toxic and generally non-toxic chemical substances. Normal responses to subtoxic doses of chemical substances may be affected under the following conditions.

Genetic and individual abnormalities in enzyme and protein synthesis. Approximately 50% of the population are slow acetylators, example : they detoxify some chemicals slowly and thus are at risk to chemical sensitivity.

  • Poor diet and deficient nutritional states
  • Obesity and or increased fat / muscle ratio.
  • Age extremities-elderly and new born
  • Disorders of kidney and liver function
  • Gender of the individual.
  • Unstable hormone status.
  • Environmental stress conditions-heat, cold, dehydration, deficiency of oxygen (asthma), noise.
  • Achlorhydria is common in many chemical sensitive individuals and hence Vitamin B12 absorption may be impaired.

Chemical sensitivity or the allergic tendency of an individual can be inherited. However, allergic tendency, with no previous family history of allergy, can also be acquired in a number of ways. Hypersensitivity may follow viral infections such as mononucleosis or viral pneumonia, or severe emotional reactions such as grief. The most common incitement appears to be low grade, long term chemical exposure, although a short term high level exposure, such as seen in industrial accidents, may produce similar effects.

There is apparently no consistent pathway by which the immune system mediates chemical hypersensitivity or loses its control mechanism and begins to sensitize inappropriately to chemicals. The pathways used by the immune system to develop this phenomenon not only vary from chemical to chemical but from exposure to exposure, and certainly differ from individual to individual.

There are also the secondary effects or pathways of allergic inflammation to be considered, for instance, gastrointestinal symptoms range from vague indigestion to full blown colitis (inflammation of the colon). These may result in nutritional deficiencies.

The deficiencies begin with increasing the sensitivity of the immune system to food. Generalised inflammation of the gastrointestinal tract secondary to food sensitivity often causes poor nutrient absorption that leads to vitamin and mineral deficiency. Eventually the individual may become deficient in digestive enzymes, which in itself will initiate food intolerance or sensitivity.

With increasing vitamin and mineral deficiency and enzyme deficiencies, the end result is an inability to detoxify chemicals giving rise to more food and chemical sensitivities. Thus a vicious cycle is set that will only be overcome by judicious supplementation of vitamins, minerals and digestive enzymes.

Common Chemical Exposures that Cause Chemical Sensitivity

  • TERPENES – These are natural, volatile chemicals released from plants. They normally give the characteristic odour or scent of the plant, e.g., odour of fresh pine needles, orange, eucalyptus, cloves, jasmine. The level of terpene exposure depends on the time of year, highest concentration occurs during the warmest part of the year.
  • HYDROCARBON FUELS – natural gas, petrol fumes, coal gas, kerosene. Gas stoves or ranges can be a source of gas leakage in homes. Parking station attendants and petrol station attendance are in the high-risk group for this type of sensitivity.
    SYNTHETIC Synthetic ripening of fruits – such as bananas may liberate potentially harmful residue of the ripening gas ethylene. Commercial coffee that is gas roasted is another example.
  • FORMALDEHYDE PRODUCTS – are notorious for their adverse reactions in sensitised individuals. Hidden sources of formaldehyde exposure are plastics, chipboard, home insulating material (foam type), nylon carpets, mouth washes, wood veneer, latex paints, detergents soaps, hair setting solutions and shampoos.
  • PERFUMES – heavily scented cosmetic, deodorants, sprays, tobacco, scented soaps, nail polish, strong cleaning solvents and synthetic clothing or garments have all been implicated in chemical sensitivity. Beauticians and hairdressers should be aware that some of their symptoms such as headaches, irritability and fatique may be due to scented products.
  • PESTICIDES – weedicides and agriculture chemicals must also be considered as potential problems in some individuals.
  • ARTIFICIAL – colourings and flavourings.
  • CHLORINATED WATER – is also a common culprit.Symptoms of chemical sensitivity vary quite widely and include headache, irritability, fatigue, hyper or overactivity, restlessness, anxiety, sluggish thinking, malaise, muscle pain, arthritis etc.

Nutrients That Decrease Chemical Sensitivity

  • Molybdenum are enzymes involved in the detoxification of various aldehydes, sulphites & nitrates.
  • Glycine, Taurine, BCAA, Methionine, are amino acids associated with the removal of toxic chemicals and metabolites from the body.
  • Thiamine (Vit B1) helps those excess intake exposure to formaldehyde, alcohols, glycols and it is also important in energy production. A relative deficiency will cause tiredness, weakness and anxiety.
  • Pyridoxine (B6), 60 percent chemically sensitive patients are deficient in B6, which is pyridoxal – 5 phosphate, which can be overwhelmed by exposure to aldehydes. Drugs such as contraceptive pills, amphetamine, chlorpromazine can all lead to a relative B6 deficiency.
  • Choline – ingestion of a diet deficient choline has major consequences that include hepatic, renal, memory impairment and growth disorders. All are seen in some chemically sensitive patients.
  • Folate B12 – chemically sensitive individuals are low in folate and 15% are deficient in Vit B12. Many medications such as aspirin, oral contraceptive and anti-convulsant interfere with absorption and metabolism.
  • Magnesium – Approximately 40% of chemically sensitive individuals are magnesium depleted. As magnesium involved over 500 enzyme systems.
  • Substances that deplete magnesium are pollutants, alcohols, diuretics, steroids, glucose, phosphate depletion and pesticides.

Nutritional Advice

  • Filter or boil all drinking water
  • Use toxic cleaning products sparingly
  • Reduce use of plastics, toxic paints and varnishes. When painting use odourless alkali based paints
  • Do not to wear synthetic under garments or clothes. Cottons & woollens are usually safe.
  • Do not use kerosene heaters, heating should be solar based or electrical.
  • An electric stove is preferable to a gas stove, and if not possible, ensure adequate ventilation within the cooking area.
  • Insulation material and floor coverings should be inert. Preferably hard, inert materials such as stone, terrazzo, hardwood, cement, brick and terracotta tiles should be used for flooring. Be careful of wool carpeting with latex or rubber backing.
  • Soft plastics, such as plastic bags, wrapping, plastic containers, and other plastics should be removed from the home. Use glass containers.
  • Remove any synthetic or rubber furnishing in the bedroom. Use cotton pillows, mattresses. Electric blanket should not be used. Cane hardwood, leather, wool or other fibre should be used in furnishings.
  • Other sources of chemical exposure are from chemicals released from glued parts and grouting, particularly when heated, chemicals used in hobbies such as photo copying machines, pesticides used indoors or in the garden, timber impregnated with chemicals, tobacco smoke.
  • Avoid all formulated foods or drugs that contain artificial flavourings, colouring or chemicals.

Fertility & Gynaecology

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Dr Ng Peng Wah
Fertility Specialist, Obstetrician and Gynaecologist Royal College of Obstetricians & Gynaecologists in United Kingdom


About Dr Ng Peng Wah
1995 – First Gamete Intrafallopian Transfer (GIFT) baby boy was born.
1996 – First In-Vitro Fertilisation (IVF) twins baby boys were born.
1999 – First Intracytoplasmic Sperm Injection (ICSI) twins baby boy and girl were born.
2001 – First frozen embryo transfer (FET) baby girl was born.
2004 – First Testicular Sperm Extraction (TESE) baby boy was born.
2007 – First blastocyst culture twins baby boy and girl were born.
From 2011 to 2012, he also served as the President of the Malaysian Society for Assisted Reproductive Technology (MSART) and remains a Committee Member till today.

关于伍柄华医生:
1995年–首例配子输卵管内植入 (GIFT) 男婴诞生。
1996年–首例试管婴儿 (IVF) 双胞胎男婴诞生。
1999年-首例胞质内精子注射 (ICSI) 双胞龙凤胎男女婴诞生。
2001年-首例冷冻胚胎移植 (FET) 女婴诞生。
2004年-首例睾丸精子提取 (TESE) 男婴诞生。
2007年-首例囊胚培养双胞龙凤胎男女婴诞生。
从2011年到2012年,伍医生也担任马来西亚辅助生育技术学会 (MSART) 的会长,直至现在依旧是该学会的委员会成员。


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Penang, which has been designated as UNESCO World Cultural Heritage Site, is repeatedly considered one of the most desirable tourist destinations in Asia. With medical tourists increasingly seeking for medical treatment in Malaysia, it is clearly seen that the healthcare services offered and delivered in Penang is of international standards.

丰盛多姿的历史背景、独特深远的文化融合,还有绝美宜居的地理环境,槟城曾多次被誉为亚洲最理想的旅游目的地之一。随着日与俱增的旅客在马来西亚寻求医疗服务,这也奠定了槟城的医疗体系的优质且符合国际标准。

Dr Ng Peng Wah, a renowned and familiar name in this region’s IVF industry has over 28 years of experience in the field of obstetrics, gynaecology and fertility. With his talents and experiences, he has numerous successes to his name and has helped thousands of patients in delivering their dreams.

Genesis IVF which is co-founded and led by Dr Ng, has quickly become the undisputed leading IVF centre in the medical tourism industry dedicated to assist patients overcome infertility. We sat down with him for a short interview.

伍柄华医生 (Dr Ng Peng Wah) 这个耳熟能详的名字,在俗称“试管婴儿” (IVF-体外受精联合胚胎移植技术) 和妇产科辅助生殖科领域拥有超过28年的经验。他的杰出才能和娴熟丰富历练,创造了许多成功的案例,并协助上千名病患实现他们的生育梦想。

由伍医生共同创立并领导的 Genesis IVF,迅速成为医疗旅游行业中一路领先的辅助生殖专科中心,致力于协助病人克服不育症。我们这次也捉紧机会和他简短会谈。

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EZ : We’ve seen an influx of international patients coming to Malaysia for better medical treatment. Has it been the same for fertility medicine?

NPW : Indeed, it has. In 2016, Malaysia is recorded to have earned RM1 billion from healthcare tourism and expected to achieve RM1.3 billion in 2017. In our centre, over 60% of our patients come from overseas. It is very assuring to know that there are so many international patients who have confidence in our IVF centre.

EZ : In your many years of practice, what are your thoughts on the Malaysia’s assisted reproductive technology, in comparison with the region?

NPW : Malaysia’s medical capabilities has seen huge improvements over the last few years. For example, Malaysian IVF in the 80s had only around 15% success rates. Today, we have reached 80% in embryo transfers. Malaysia is also now deemed having one of the most comprehensive and complete all-in-one fertility services in Asia and Australia.

EZ : What drove you to establish Genesis IVF?

NPW : Throughout the years, I’ve seen patients from all walks of life and the joy of finally helping patients overcome infertility is the greatest pleasure I can experience. I believe with Genesis IVF, we are providing a centre that has an all-inclusive service for all their infertility needs. Our patients are able to receive first class comfort and professional care.

EZ : We understand Genesis IVF has its very own laboratory. Can you tell us more?

NPW : Of course! Genesis IVF has its own team of talented embryologists and geneticists. We are not only focused on increasing the chances of couples to have a baby, but we believe in creating healthy future generations. Our lab is fully capable of providing Pre-implantation Genetic Screening (PGS) as well as Pre-implantation Genetic Diagnosis (PGD) to select the best healthy embryo for each couple.

With PGS, we are able to analyse the 23 pairs of chromosomes in the embryo’s DNA and increase the chance of pregnancy while reducing the risk of miscarriage or risk of having a chromosomally abnormal child.

PGD is recommended for couples who have a known genetic abnormality, such as Thalassaemia. With PGD, we are able to help reduce the chances of their children inheriting any genetic abnormalities.

EZ : Many couples are getting married and planning to start a family later these days. What is your advice?

NPW : While there is a saying that “30 is the new 20”, our body’s biological age hasn’t changed much yet. Studies have shown women above the age 35 have a significantly increased risk of infertility.

Fortunately, we are here to help. Our modern lifestyle is also a contributing factor to infertility. Remember to take everything in moderation and seek a balanced diet.

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EZ : 我们看到大量的国际病患者前来马来西亚寻求更好的医疗服务,对于生育医学领域来说也是这种情况吗?

NPW : 确实。在2016年,马来西亚的医疗旅游收入超过10亿令吉。而在我们的医疗中心,60%以上的病人皆来自海外。我们也非常肯定,许多国际患者对于 Genesis IVF 专科中心充满信心。

EZ : 依据多年的实践经验,你对马来西亚辅助生育技术有何看法?与该区域之间相比?

NPW : 马来西亚医疗技术质量在过去几年里取得了巨大的进展。例如,我们80年代试管婴儿成功率只有15%左右。今天,胚胎移植率已达到80%,同时也被认为是在亚洲与澳大利亚区域间具备最全面生育服务的国家之一。

EZ : 驱使你创立 Genesis IVF 的动力是什么?

NPW : 多年来我接触到形形色色的患者,帮助他们克服不育症的喜悦,让我能感受到的美好快乐。我相信 Genesis IVF 中心提供全面的辅助生殖疗程。我们的病人在最佳的舒适环境和得到专业照顾。

EZ : 我们知道 Genesis IVF 有本身独立的实验室。对此我们可以了解更多吗?

NPW : 当然!Genesis IVF 拥有一组具备天赋的胚胎学家和遗传学家的团队。我们不仅关注增加夫妻孕育孩子的机会,而且我们确定创造健康的后代。我们的实验室拥有提供胚胎植入前遗传基因筛查 (PGS) 和胚胎植入前遗传基因诊断 (PGD) 的实践能力,为每对夫妇遴选出最佳状态的健康胚胎。

透过PGS筛选,我们能够检查胚胎基因中的23对染色体,促进怀孕的机率,同时极力降低流产的风险或者孕育染色体异常的孩子。

至于PGD诊断适合携带已知基因异常的夫妻,比如地中海贫血。通过PGD的排除,我们能够帮助减少他们的孩子遗传任何基因异常或缺陷的状况。

EZ : 对于那些近期结婚并计划组织小家庭的夫妻,你的建议是什么?

NPW : 纵然目前有个说法是“30代是新20代”,但我们的身体机能年龄还是无太多变化。研究证明,35岁以上的女性面临不孕的风险大幅度增加。幸运的是,我们可提供帮助。现代人的生活方式也是导致不育症的因素之一,记住必须坚守节制的生活习惯和均衡饮食。

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